Researcher at the Department of Biomedicine

Arbeidsgiver Universitetet i Bergen Stillingstittel Research scientist Frist 25.10.2023 Ansettelsesform Fast

Bli kjent med Universitetet i Bergen

Researcher at the Department of Biomedicine UiB - Knowledge that shapes societyThrough robust and close interaction with the world around us - globally, nationally and locally - we shall be instrumental in building a society based on knowledge, skills and attitudes.Do you want to take part in shaping the future?Research scientist At the Faculty of Medicine, Department of Biomedicine, a full-time permanent position as researcher is available. The position is associated with the large, interdisciplinary research project "Hub Molecules of Life" (HubMOL), which is jointly financed by the NFR and the University of Bergen. The project has a temporary financing for 3 years.About the project/work tasks:In all living organisms, there is a subset of small coenzyme molecules that participate in thousands of biochemical reactions, thereby enabling and coordinating metabolism. In the course of evolution, the same molecules have attained more and more key roles as regulators of virtually all biological processes. HubMOL aims to unravel the mechanistic principles of how these molecules of life interact to enable and control both metabolism and signaling. The project combines world-leading competences in synthetic and analytical chemistry, biochemistry, molecular genetics, bioinformatics and advanced technology development. Through their direct association with established medical research centers (NeuroSysMed with a focus on neurodegeneration, KG Jebsen Center on Parkinson's Disease), the core scientists will closely collaborate with clinicians to apply the findings from basic research to disease diagnostics and treatment.The successful candidate will work in the group of Prof. Mathias Ziegler at the Department of Biomedicine, who is leading studies on metabolism and signaling, closely collaborating with Prof. Ines Heiland, who is an expert in metabolic modeling.The successful candidate is expected to lead this sub-project with diligence and a high level of independence, initiative and problem-solving capacity. The position will require being constantly updated with methodological developments and advances in the field. At the same time, this position will offer substantial opportunities for career development and growth. The candidate will work with state-of-the-art analytical instrumentation, generate extensive experimental data sets and analyze them using advanced bioinformatics methods.Other work tasks:Designing in-vitro experiments using recombinant enzymes in order to investigate catalytic properties of key enzymesDesigning cell culture experiments suitable for investigating mechanistic principles of how small molecules, such as NAD, control processes related to metabolism and signalingDeveloping methodological approaches for generating high quality biological samples, suitable for - omics analysis, from cell cultureDeveloping LC-MS based methods for generating high quality data from biological samplesConducting fluxomics experiments including stable isotope labeling, prepare and run samples on LCMS-MS, correct for naturally occurring isotopes and run corresponding large-scale data analysesQualifications and personal qualities:Absolute requirements:The applicant must hold a relevant Norwegian PhD or equivalent doctoral degreeDocumented broad knowledge of metabolic pathways, ideally, in NAD metabolism Proven competence in advanced methods for metabolomics and fluxomics analyses of biological samples, in particular, LC-MS (both Orbitrap and QQQ MS instrumentation)Experience with bioinformatic tools to process LC-MS dataTrack record of peer-reviewed publications in internationally renowned journalsExcellent verbal and written communication skillsFluent verbal and written english language skills The following skills would be advantageous:Experience working with cell culture and genetic engineering (CRISPR-Cas etc.)Expertise in development of methodological approaches for targeted and untargeted LC-MS analysis of biological samplesDocumented competence in enzymology and protein chemistry, experience working with recombinant proteins Familiarity with the use of stable isotope labeling in metabolomicsAn interest in metabolic modelingExperience in teaching at university levelDemonstrated ability to work independently within an international environment.Proven problem-solving skills, collaborative nature, and adaptability across disciplines We can offer:An excellent and challenging work environment in research front of metabolism and signalingSalary NOK 635 400 (code 1109, pay grade 65), specialist NOK 657 300 (code 1109, pay grade 67) gross p.a. for a fulltime position. In the case of a highly qualified applicant, a higher salary may be considered.Enrolment in the Norwegian Public Service Pension Fund (https://www.spk.no/en/)Good welfare benefits (https://www.uib.no/en/foremployees/30808/welfare)Your application must include:A brief letter of application stating your motivation for the position, why you are applying and why this position is perfect for youAn overview of your education and work experience (CV)Witnessed copies of diplomas and relevant certificates (applicants with education from other countries than Norway must enclose diplomas in both the original language and authorized translations)Publications and academic work (max 10 in PDF) and a list of these • Your PhD thesis (in PDF)Two references (name and contact information)It is very important that each of the scholarly works on which the committee should place special emphasis, is attached in its entirety.The application and any attachments along with certified translations in English or another Scandinavian language must be uploaded to JobbNorge.On the basis of this information, the expert committee will undertake a review of the applicants. The following premise forms the basis for the post as research scientist:The researcher will be a member of the research group of which the topic/project belongs toThe salary shall if possible be 100 % covered by external financingThe researcher shall actively contribute to attract external funding to the research project, both for her/his own position and other positions, from the Research Council of Norway, EU and other sourcesThe researcher is expected to have her/his research activity financed by the project of the researcher and the projects of the associated research groupThe Head of Department may allocate work for the Researcher related to specific research projectsThe researcher may participate in committee work and other administrative tasks within the University of BergenThe researcher has no teaching duties, but is expected to supervise master students and PhD candidates when this is a natural part of the research activity of the research groupThe researcher may apply for competence promotion according to the regulations for promotionsThe basis for the position ceases if no further project funding and new law on state officials etc. on dismissal and preferential rights will be applied to permanent employeesGeneral information:Further information about the position can be obtained from: Professor Mathias Ziegler, phone: +4755584591 or e-mail: mathias.ziegler@uib.noThe state workforce shall reflect the diversity of Norwegian society to the greatest extent possible. People with immigrant backgrounds and people with disabilities are encouraged to apply for the position.UiB must follow Norway's export control regulations when processing applications for this position. The University of Bergen applies the principles of public access to information when recruiting staff for academic positions.Information about applicants may be made public even if the applicant has asked not to be named in the list of persons who have applied. The applicant must be notified if the request to be omitted is not met.For further information about the recruitment process, click here (https://www.uib.no/en/hr/74459/appointment-process).

Om arbeidsgiveren The University of Bergen is a renowned educational and research institution, organised into seven faculties and approximately 54 institutes and academic centres. Campus is located in the centre of Bergen with university areas at Nygårdshøyden, Haukeland, Marineholmen, Møllendalsveien and Årstad. There are five departments and eight centres at Faculty of Medicine.Read More about the faculty and departments.

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